Science and Technology
2019
Biotechnology Basics
Genetic Engineering
Agricultural Technology
Health and Diseases

‘RNA interference (RNAi)’ technology has gained popularity in the last few years. Why?

  1. It is used in developing gene silencing therapies.
  2. It can be used in developing therapies for-the treatment of cancer.
  3. It can be used to develop hormone replacement therapies.
  4. It can be used to produce crop plants that are resistant to viral pathogens.

Select the correct answer using the code given below.

B.2 and 3
C.1 and 3
D.1 and 4 only
A.1, 2 and 4

Correct Answer: Option A

RNA interference (RNAi) is a biological process where RNA molecules inhibit gene expression or translation, leading to gene silencing.

Statement 1 is correct: RNAi is indeed used in developing gene silencing therapies by suppressing the expression of specific genes.

Statement 2 is correct: RNAi shows potential in cancer treatment by targeting cancer-related genes (oncogenes) and inhibiting tumor growth.

Statement 3 is incorrect: RNAi is not typically used for hormone replacement therapies.

Statement 4 is correct: RNAi is used to develop crop plants resistant to viral pathogens. Introducing short, non-coding regions of viral RNA sequences into plants can provide protection against viral infections through virus-induced gene silencing (VIGS).

Therefore, statements 1, 2, and 4 are correct.

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