In the context of hereditary diseases, consider the following statements :

1. Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg.
2. A child inherits mitochondrial diseases entirely from mother and not from father. Which of the statements given above is/are correct?

Mitochondrial Replacement Therapy (MRT) is a specialized in-vitro fertilization (IVF) technique designed to prevent the transmission of mitochondrial diseases from mother to child.

MRT involves replacing a woman's affected mitochondrial DNA (mtDNA) with healthy mtDNA from a donor.

This replacement can occur either before or shortly after fertilization, but always before the fertilized egg develops into an embryo.

Techniques like Spindle Transfer (ST), Pronuclear Transfer (PNT), and Polar Body Transfer (PBT) are used in MRT.

The primary goal of MRT is to produce a healthy baby free from inherited mitochondrial disorders.

In mammals, including humans, the mitochondrial genome is inherited almost exclusively from the mother.

Therefore, the transmission of paternal mitochondria or mitochondrial DNA (mtDNA) is negligible.

Statement 1 is correct. Statement 2 is correct.

Hence, both statements 1 and 2 are correct.